MitoProteome Database

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MT001555

UniProt Annotations

Entry Information

Gene Name	acyl-CoA synthetase medium-chain family member 6
Protein Entry	ACSM6_HUMAN
UniProt ID	Q6P461
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q6P461-1; Sequence=Displayed; Name=2; IsoId=Q6P461-2; Sequence=VSP_033908, VSP_033910, VSP_033911; Note=No experimental confirmation available.; Name=3; IsoId=Q6P461-3; Sequence=VSP_033909; Note=No experimental confirmation available.;
Catalytic Activity	ATP + a carboxylate + CoA = AMP + diphosphate + an acyl-CoA.
Cofactor	Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Sequence Caution	Sequence=AAI04211.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI04212.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI12989.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAH72344.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity	Belongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.
Subcellular Location	Mitochondrion {ECO:0000305}.
Subunit	Monomer. {ECO:0000250}.