MitoProteome Database

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MT001571

UniProt Annotations

Entry Information

Gene Name	aldehyde dehydrogenase 1 family, member L2
Protein Entry	AL1L2_HUMAN
UniProt ID	Q3SY69
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q3SY69-1; Sequence=Displayed; Name=2; IsoId=Q3SY69-2; Sequence=VSP_030752, VSP_030753; Note=No experimental confirmation available.; Name=3; IsoId=Q3SY69-3; Sequence=VSP_030754, VSP_030755; Note=No experimental confirmation available.;
Catalytic Activity	10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.
Sequence Caution	Sequence=AAI03936.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
Similarity	Contains 1 acyl carrier domain. {ECO:0000255\|PROSITE- ProRule:PRU00258}.
Similarity	In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. {ECO:0000305}.
Similarity	In the N-terminal section; belongs to the GART family. {ECO:0000305}.
Subcellular Location	Mitochondrion {ECO:0000269\|PubMed:20498374}.
Tissue Specificity	Highly expressed in pancreas, heart, brain and skeletal muscle. {ECO:0000269\|PubMed:20498374}.