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MT001613

Record overview

MITO ID	MT001613
Gene ID	267012
Species	Homo sapiens (Human)
Gene Name	D-amino acid oxidase activator
Gene Symbol	DAOA
Synonyms	LG72; SG72;
Alternate names	D-amino acid oxidase activator; G72 transcript; schizophrenia- and bipolar disorder-associated protein G72;
Chromosome	13
Map Location	13q33.2
Summary	This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011]
Orthologs	View orthologs and multiple alignments for DAOA

Proteins

D-amino acid oxidase activator isoform 1

Refseq ID:	NP_758958
Protein GI:	126362975
UniProt ID:	P59103
mRNA ID:	NM_172370
Length:	153
RefSeq Status:

D-amino acid oxidase activator isoform 2
`MLEKLMGADSLQLFRSRYTLGKIYFIGFQRSILLSKSENSLNSIAKETEEGRETVTRKEGWKRRHEDGYLEMAQRHLQRSLCPWVSYLPQPYAELEEVSS HVGKVFMARNYEFLAYEASKDRRQPLERMWTCNYNQQKDQSCNHKEITSTKAE`

Refseq ID:	NP_001155284
Protein GI:	240120173
UniProt ID:	P59103
mRNA ID:	NM_001161812
Length:	125
RefSeq Status:

D-amino acid oxidase activator isoform 3
`MRTAIWKWHRGIYRDHYVLGSLTFLSPMQRAGTSNQWNMGKVMTLDSGDEVTFHKTWPTETGSPYRLEEVSSHVGKVFMARNYEFLAYEASKDRRQPLER MWTCNYNQQKDQSCNHKEITSTKAE`

Refseq ID:	NP_001155286
Protein GI:	240120029
UniProt ID:	P59103
mRNA ID:	NM_001161814
Length:	82
RefSeq Status:

`MAQRHLQRSLCPWVSYLPQPYAELEEVSSHVGKVFMARNYEFLAYEASKDRRQPLERMWTCNYNQQKDQSCNHKEITSTKAE`