MitoProteome Database

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MT001614

UniProt Annotations

Entry Information

Gene Name	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
Protein Entry	AT5L2_HUMAN
UniProt ID	Q7Z4Y8
Species	Human

Comments

Comment type	Description
Caution	Could be the product of a pseudogene. {ECO:0000305}.
Function	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity). {ECO:0000250}.
Similarity	Belongs to the ATPase g subunit family. {ECO:0000305}.
Subcellular Location	Mitochondrion membrane {ECO:0000250}.
Subunit	F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) seems to have nine subunits: a, b, c, d, e, f, g, F6 and 8 (or A6L).