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MT001686

Gene Information

Entrez Gene ID	728294
Gene Name	D-2-hydroxyglutarate dehydrogenase
Gene Symbol	D2HGDH
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005759	TAS:Reactome	C	mitochondrial matrix
GO:0005739	ISS:HGNC	C	mitochondrion
GO:0050660	IEA:InterPro	F	flavin adenine dinucleotide binding
GO:0051990	ISS:HGNC	F	(R)-2-hydroxyglutarate dehydrogenase activity
GO:0008762	IEA:InterPro	F	UDP-N-acetylmuramate dehydrogenase activity
GO:0006103	TAS:Reactome	P	2-oxoglutarate metabolic process
GO:0044237	TAS:Reactome	P	cellular metabolic process
GO:0044267	ISS:HGNC	P	cellular protein metabolic process
GO:0032025	ISS:HGNC	P	response to cobalt ion
GO:0010042	ISS:HGNC	P	response to manganese ion
GO:0010043	ISS:HGNC	P	response to zinc ion
GO:0044281	TAS:Reactome	P	small molecule metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_25367	Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
REACT_111217	Metabolism
REACT_1046	Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_111083	The citric acid (TCA) cycle and respiratory electron transport