MitoProteome Database

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MT000018

Gene Information

Entrez Gene ID189
Gene Namealanine-glyoxylate aminotransferase
Gene SymbolAGXT
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005759 IEA:EnsemblCmitochondrial matrix
GO:0005782 IDA:UniProtKBCperoxisomal matrix
GO:0005777 IDA:UniProtKBCperoxisome
GO:0008453 IDA:UniProtKBFalanine-glyoxylate transaminase activity
GO:0016597 IDA:UniProtKBFamino acid binding
GO:0042803 IDA:UniProtKBFprotein homodimerization activity
GO:0030170 IDA:UniProtKBFpyridoxal phosphate binding
GO:0005102 IPI:UniProtKBFreceptor binding
GO:0004760 IEA:UniProtKB-ECFserine-pyruvate transaminase activity
GO:0008483 IDA:UniProtKBFtransaminase activity
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0019265 IDA:UniProtKBPglycine biosynthetic process, by transamination of glyoxylate
GO:0009436 IDA:UniProtKBPglyoxylate catabolic process
GO:0046487 IMP:HGNCPglyoxylate metabolic process
GO:0042853 IDA:UniProtKBPL-alanine catabolic process
GO:0019448 IDA:UniProtKBPL-cysteine catabolic process
GO:0046724 IEA:EnsemblPoxalic acid secretion
GO:0042866 IEA:EnsemblPpyruvate biosynthetic process
GO:0051591 IEA:EnsemblPresponse to cAMP
GO:0051384 IEA:EnsemblPresponse to glucocorticoid
GO:0044281 TAS:ReactomePsmall molecule metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00250Alanine, aspartate and glutamate metabolism
ko00250Alanine, aspartate and glutamate metabolism
hsa01200Carbon metabolism
ko01200Carbon metabolism
hsa00260Glycine, serine and threonine metabolism
ko00260Glycine, serine and threonine metabolism
hsa00630Glyoxylate and dicarboxylate metabolism
ko00630Glyoxylate and dicarboxylate metabolism
hsa01100Metabolic pathways
hsa04146Peroxisome
ko04146Peroxisome
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
GLYSYN-ALA-PWYglycine biosynthesis III
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_16925Glyoxylate metabolism
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives