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MT000027

Record overview

MITO IDMT000027
Gene ID219
SpeciesHomo sapiens (Human)
Gene Namealdehyde dehydrogenase 1 family, member B1
Gene SymbolALDH1B1
SynonymsALDH5; ALDHX;
Alternate namesaldehyde dehydrogenase X, mitochondrial; ALDH class 2; aldehyde dehydrogenase 5; acetaldehyde dehydrogenase 5;
Chromosome9
Map Location9p11.1
EC Number1.2.1.3
SummaryThis protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ALDH1B1

Proteins

aldehyde dehydrogenase X, mitochondrial precursor
Refseq ID:NP_000683
Protein GI:25777730
UniProt ID:P30837
mRNA ID:NM_000692
Length:517
RefSeq Status:
MLRFLAPRLLSLQGRTARYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASE
RGRLLNRLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPAL
ATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADM
EHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKP
TVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLK
AYTEVKTVTIKVPQKNS
 
N
transit_peptide: 1..17
calculated_mol_wt: 1943
peptide sequence: 
MLRFLAPRLLSLQGRTA

mat_peptide: 18..517
product: aldehyde dehydrogenase X, mitochondrial
calculated_mol_wt: 55324
peptide sequence: 
RYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRV
YLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLS
ALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQ
CCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDMRIAKEEI
FGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS