MitoProteome Database

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MT000040

Gene Information

Entrez Gene ID369
Gene NameA-Raf proto-oncogene, serine/threonine kinase
Gene SymbolARAF
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004672 TAS:ProtIncFprotein kinase activity
GO:0004674 IDA:UniProtKBFprotein serine/threonine kinase activity
GO:0005057 IEA:InterProFreceptor signaling protein activity
GO:0006464 TAS:ProtIncPcellular protein modification process
GO:0043066 IDA:UniProtKBPnegative regulation of apoptotic process
GO:0033138 IDA:UniProtKBPpositive regulation of peptidyl-serine phosphorylation
GO:0032434 IMP:UniProtKBPregulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032006 IMP:UniProtKBPregulation of TOR signaling
KEGG Pathway Links
KEGG Pathway IDDescription
hsa05221Acute myeloid leukemia
ko05221Acute myeloid leukemia
hsa05034Alcoholism
ko05034Alcoholism
hsa05219Bladder cancer
ko05219Bladder cancer
hsa05220Chronic myeloid leukemia
ko05220Chronic myeloid leukemia
hsa05210Colorectal cancer
ko05210Colorectal cancer
hsa05213Endometrial cancer
ko05213Endometrial cancer
hsa04012ErbB signaling pathway
ko04012ErbB signaling pathway
hsa04068FoxO signaling pathway
hsa05214Glioma
ko05214Glioma
hsa05160Hepatitis C
ko05160Hepatitis C
hsa04910Insulin signaling pathway
ko04910Insulin signaling pathway
hsa04730Long-term depression
ko04730Long-term depression
hsa04720Long-term potentiation
ko04720Long-term potentiation
hsa05218Melanoma
ko05218Melanoma
hsa04650Natural killer cell mediated cytotoxicity
ko04650Natural killer cell mediated cytotoxicity
hsa05223Non-small cell lung cancer
ko05223Non-small cell lung cancer
hsa05212Pancreatic cancer
ko05212Pancreatic cancer
hsa05200Pathways in cancer
hsa04914Progesterone-mediated oocyte maturation
ko04914Progesterone-mediated oocyte maturation
hsa05215Prostate cancer
ko05215Prostate cancer
hsa05205Proteoglycans in cancer
ko05205Proteoglycans in cancer
hsa04810Regulation of actin cytoskeleton
ko04810Regulation of actin cytoskeleton
hsa05211Renal cell carcinoma
ko05211Renal cell carcinoma
hsa04726Serotonergic synapse
hsa04270Vascular smooth muscle contraction
ko04270Vascular smooth muscle contraction