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MT000064

Record overview

MITO IDMT000064
Gene ID539
SpeciesHomo sapiens (Human)
Gene NameATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
Gene SymbolATP5O
SynonymsATPO; OSCP;
Alternate namesATP synthase subunit O, mitochondrial; human ATP synthase OSCP subunit; oligomycin sensitivity conferral protein; oligomycin sensitivity conferring protein;
Chromosome21
Map Location21q22.11
SummaryThe protein encoded by this gene is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ATP5O

Proteins

ATP synthase subunit O, mitochondrial precursor
Refseq ID:NP_001688
Protein GI:4502303
UniProt ID:P48047
mRNA ID:NM_001697
Length:213
RefSeq Status:
MAAPAVSGLSRQVRCFSTSVVRPFAKLVRPPVQVYGIEGRYATALYSAASKQNKLEQVEKELLRVAQILKEPKVAASVLNPYVKRSIKVKSLNDITAKER
FSPLTTNLINLLAENGRLSNTQGVVSAFSTMMSVHRGEVPCTVTSASPLEEATLSELKTVLKSFLSQGQVLKLEAKTDPSILGGMIVRIGEKYVDMSVKT
KIQKLGRAMREIV
 
N
transit_peptide: 1..23
calculated_mol_wt: 2420
peptide sequence: 
MAAPAVSGLSRQVRCFSTSVVRP

mat_peptide: 24..213
product: ATP synthase subunit O, mitochondrial
calculated_mol_wt: 20876
peptide sequence: 
FAKLVRPPVQVYGIEGRYATALYSAASKQNKLEQVEKELLRVAQILKEPKVAASVLNPYVKRSIKVKSLNDITAKERFSPLTTNLINLLAENGRLSNTQG
VVSAFSTMMSVHRGEVPCTVTSASPLEEATLSELKTVLKSFLSQGQVLKLEAKTDPSILGGMIVRIGEKYVDMSVKTKIQKLGRAMREIV