MitoProteome Database

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MT000105

Gene Information

Entrez Gene ID840
Gene Namecaspase 7, apoptosis-related cysteine peptidase
Gene SymbolCASP7
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 TAS:ProtIncCcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0004197 IBA:RefGenomeFcysteine-type endopeptidase activity
GO:0008234 TAS:ProtIncFcysteine-type peptidase activity
GO:0008635 TAS:ReactomePactivation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0006915 TAS:ReactomePapoptotic process
GO:0006921 TAS:ReactomePcellular component disassembly involved in execution phase of apoptosis
GO:0097194 IBA:RefGenomePexecution phase of apoptosis
GO:0097193 TAS:ReactomePintrinsic apoptotic signaling pathway
GO:0006508 IDA:UniProtKBPproteolysis
KEGG Pathway Links
KEGG Pathway IDDescription
hsa05010Alzheimer's disease
ko05010Alzheimer's disease
hsa04210Apoptosis
ko04210Apoptosis
hsa05134Legionellosis
ko05134Legionellosis
hsa04932Non-alcoholic fatty liver disease (NAFLD)
ko04932Non-alcoholic fatty liver disease (NAFLD)
hsa05133Pertussis
ko05133Pertussis
hsa04668TNF signaling pathway
ko04668TNF signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_607Activation of caspases through apoptosome-mediated cleavage
REACT_578Apoptosis
REACT_107Apoptotic cleavage of cellular proteins
REACT_995Apoptotic execution phase
REACT_963Apoptotic factor-mediated response
REACT_13541Caspase-mediated cleavage of cytoskeletal proteins
REACT_831Cytochrome c-mediated apoptotic response
REACT_964Intrinsic Pathway for Apoptosis
REACT_2190SMAC binds to IAPs
REACT_666SMAC-mediated apoptotic response
REACT_1767SMAC-mediated dissociation of IAP:caspase complexes