MitoProteome Database

MT000109

Gene Information

Entrez Gene ID	847
Gene Name	catalase
Gene Symbol	CAT
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	IEA:Ensembl	C	cytosol
GO:0005783	IEA:Ensembl	C	endoplasmic reticulum
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005925	IDA:UniProtKB	C	focal adhesion
GO:0005794	IEA:Ensembl	C	Golgi apparatus
GO:0043231	IDA:HPA	C	intracellular membrane-bounded organelle
GO:0005764	IEA:Ensembl	C	lysosome
GO:0016020	IDA:UniProtKB	C	membrane
GO:0005758	IEA:Ensembl	C	mitochondrial intermembrane space
GO:0005782	TAS:Reactome	C	peroxisomal matrix
GO:0005778	ISS:UniProtKB	C	peroxisomal membrane
GO:0005777	IDA:UniProtKB	C	peroxisome
GO:0005886	IEA:Ensembl	C	plasma membrane
GO:0004046	IEA:Ensembl	F	aminoacylase activity
GO:0016209	IDA:UniProtKB	F	antioxidant activity
GO:0004096	IDA:UniProtKB	F	catalase activity
GO:0019899	IPI:UniProtKB	F	enzyme binding
GO:0020037	IDA:UniProtKB	F	heme binding
GO:0046872	IEA:UniProtKB-KW	F	metal ion binding
GO:0050661	IDA:UniProtKB	F	NADP binding
GO:0016684	ISS:UniProtKB	F	oxidoreductase activity, acting on peroxide as acceptor
GO:0042803	IDA:UniProtKB	F	protein homodimerization activity
GO:0005102	IPI:UniProtKB	F	receptor binding
GO:0009060	IEA:Ensembl	P	aerobic respiration
GO:0071363	IEA:Ensembl	P	cellular response to growth factor stimulus
GO:0008203	IEA:Ensembl	P	cholesterol metabolic process
GO:0020027	IEA:Ensembl	P	hemoglobin metabolic process
GO:0042744	IDA:UniProtKB	P	hydrogen peroxide catabolic process
GO:0042697	IEA:Ensembl	P	menopause
GO:0043066	IMP:UniProtKB	P	negative regulation of apoptotic process
GO:0032088	IEA:Ensembl	P	negative regulation of NF-kappaB transcription factor activity
GO:0055086	TAS:Reactome	P	nucleobase-containing small molecule metabolic process
GO:0001649	IDA:UniProt	P	osteoblast differentiation
GO:0051781	IEA:UniProtKB-KW	P	positive regulation of cell division
GO:0051092	IEA:Ensembl	P	positive regulation of NF-kappaB transcription factor activity
GO:0014068	IEA:Ensembl	P	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051289	IDA:UniProtKB	P	protein homotetramerization
GO:0051262	IDA:UniProtKB	P	protein tetramerization
GO:0006144	TAS:Reactome	P	purine nucleobase metabolic process
GO:0006195	TAS:Reactome	P	purine nucleotide catabolic process
GO:0055093	IEA:Ensembl	P	response to hyperoxia
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0000302	IMP:UniProtKB	P	response to reactive oxygen species
GO:0033197	IEA:Ensembl	P	response to vitamin E
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0006641	IEA:Ensembl	P	triglyceride metabolic process
GO:0001657	IEA:Ensembl	P	ureteric bud development
GO:0009650	IMP:UniProtKB	P	UV protection

KEGG Pathway Links

KEGG Pathway ID	Description
hsa05014	Amyotrophic lateral sclerosis (ALS)
ko05014	Amyotrophic lateral sclerosis (ALS)
hsa04068	FoxO signaling pathway
hsa00630	Glyoxylate and dicarboxylate metabolism
ko00630	Glyoxylate and dicarboxylate metabolism
hsa04146	Peroxisome
ko04146	Peroxisome
hsa00380	Tryptophan metabolism
ko00380	Tryptophan metabolism

BIOCYC Pathway Links

BIOCYC Pathway ID	Description
PWY66-162	ethanol degradation IV
PWY66-162	ethanol degradation IV
DETOX1-PWY	superoxide radicals degradation

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_120956	Cellular responses to stress
REACT_172715	Detoxification of Reactive Oxygen Species
REACT_111217	Metabolism
REACT_1698	Metabolism of nucleotides
REACT_2086	Purine catabolism
REACT_522	Purine metabolism