MitoProteome Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins

MT000112

UniProt Annotations

Entry Information

Gene Name	cholecystokinin
Protein Entry	CCKN_HUMAN
UniProt ID	P06307
Species	Human

Comments

Comment type	Description
Function	This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Ptm	The precursor is cleaved by proteases to produce a number of active cholecystokinins.
Similarity	Belongs to the gastrin/cholecystokinin family. {ECO:0000305}.
Subcellular Location	Secreted.
Subunit	Binds to CCK-A receptors in the pancreas and CCK-B receptors in the brain. {ECO:0000250}.
Web Resource	Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/cck/";
Web Resource	Name=Wikipedia; Note=Cholecystokinin entry; URL="http://en.wikipedia.org/wiki/Cholecystokinin";