MitoProteome Database

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MT000114

Gene Information

Entrez Gene ID1022
Gene Namecyclin-dependent kinase 7
Gene SymbolCDK7
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005675 IDA:UniProtKBCholo TFIIH complex
GO:0005739 IDA:HPACmitochondrion
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:HPACnucleus
GO:0050681 NAS:UniProtKBFandrogen receptor binding
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004693 TAS:ProtIncFcyclin-dependent protein serine/threonine kinase activity
GO:0008094 IDA:UniProtKBFDNA-dependent ATPase activity
GO:0008022 IPI:UniProtKBFprotein C-terminus binding
GO:0004672 TAS:ProtIncFprotein kinase activity
GO:0008353 IDA:UniProtKBFRNA polymerase II carboxy-terminal domain kinase activity
GO:0003713 NAS:UniProtKBFtranscription coactivator activity
GO:0006370 TAS:ReactomeP7-methylguanosine mRNA capping
GO:0030521 NAS:UniProtKBPandrogen receptor signaling pathway
GO:0006200 IDA:GOCPATP catabolic process
GO:0007050 TAS:UniProtKBPcell cycle arrest
GO:0051301 IEA:UniProtKB-KWPcell division
GO:0008283 TAS:ProtIncPcell proliferation
GO:0006281 TAS:ReactomePDNA repair
GO:0000082 TAS:ReactomePG1/S transition of mitotic cell cycle
GO:0000086 TAS:ReactomePG2/M transition of mitotic cell cycle
GO:0010467 TAS:ReactomePgene expression
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0006289 TAS:ReactomePnucleotide-excision repair
GO:0000718 TAS:ReactomePnucleotide-excision repair, DNA damage removal
GO:0045893 NAS:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0045944 IDA:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0050434 TAS:ReactomePpositive regulation of viral transcription
GO:0000079 TAS:ProtIncPregulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006363 TAS:ReactomePtermination of RNA polymerase I transcription
GO:0006283 TAS:ReactomePtranscription-coupled nucleotide-excision repair
GO:0006368 TAS:ReactomePtranscription elongation from RNA polymerase II promoter
GO:0006362 TAS:ReactomePtranscription elongation from RNA polymerase I promoter
GO:0006366 IDA:UniProtKBPtranscription from RNA polymerase II promoter
GO:0006360 TAS:ReactomePtranscription from RNA polymerase I promoter
GO:0006367 TAS:ReactomePtranscription initiation from RNA polymerase II promoter
GO:0006361 TAS:ReactomePtranscription initiation from RNA polymerase I promoter
GO:0016032 TAS:ReactomePviral process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa03022Basal transcription factors
ko03022Basal transcription factors
hsa04110Cell cycle
ko04110Cell cycle
hsa_M00290Holo-TFIIH complex
M00290Holo-TFIIH complex
hsa03420Nucleotide excision repair
ko03420Nucleotide excision repair
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_1857Cyclin A/B1 associated events during G2/M transition
REACT_9029Cyclin A:Cdk2-associated events at S phase entry
REACT_821Cyclin D associated events in G1
REACT_1574Cyclin E associated events during G1/S transition
REACT_116125Disease
REACT_216DNA Repair
REACT_311Dual incision reaction in GG-NER
REACT_2222Dual incision reaction in TC-NER
REACT_200857Epigenetic regulation of gene expression
REACT_6346Formation of HIV-1 elongation complex containing HIV-1 Tat
REACT_22201Formation of HIV elongation complex in the absence of HIV Tat
REACT_257Formation of incision complex in GG-NER
REACT_1845Formation of RNA Pol II elongation complex
REACT_846Formation of the Early Elongation Complex
REACT_6319Formation of the HIV-1 Early Elongation Complex
REACT_1941Formation of transcription-coupled NER (TC-NER) repair complex
REACT_1590G1 Phase
REACT_1783G1/S Transition
REACT_2203G2/M Transition
REACT_71Gene Expression
REACT_2253Global Genomic NER (GG-NER)
REACT_6185HIV Infection
REACT_6256HIV Life Cycle
REACT_6274HIV Transcription Elongation
REACT_6332HIV Transcription Initiation
REACT_6361Late Phase of HIV Life Cycle
REACT_21267Mitotic G1-G1/S phases
REACT_21391Mitotic G2-G2/M phases
REACT_1470mRNA Capping
REACT_200834Negative epigenetic regulation of rRNA expression
REACT_200856NoRC negatively regulates rRNA expression
REACT_1826Nucleotide Excision Repair
REACT_6237RNA Pol II CTD phosphorylation and interaction with CE
REACT_975RNA Pol II CTD phosphorylation and interaction with CE
REACT_2204RNA Polymerase I Chain Elongation
REACT_6253RNA Polymerase II HIV Promoter Escape
REACT_22107RNA Polymerase II Pre-transcription Events
REACT_2089RNA Polymerase II Promoter Escape
REACT_1366RNA Polymerase II Transcription
REACT_833RNA Polymerase II Transcription Elongation
REACT_1851RNA Polymerase II Transcription Initiation
REACT_834RNA Polymerase II Transcription Initiation And Promoter Clearance
REACT_1655RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
REACT_1974RNA Polymerase I Promoter Clearance
REACT_1913RNA Polymerase I Promoter Escape
REACT_21352RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
REACT_1309RNA Polymerase I Transcription
REACT_953RNA Polymerase I Transcription Initiation
REACT_1074RNA Polymerase I Transcription Termination
REACT_899S Phase
REACT_6162Tat-mediated elongation of the HIV-1 transcript
REACT_1628Transcription-coupled NER (TC-NER)
REACT_6233Transcription of the HIV genome