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MT000119

Record overview

MITO IDMT000119
Gene ID1152
SpeciesHomo sapiens (Human)
Gene Namecreatine kinase, brain
Gene SymbolCKB
SynonymsBCK; B-CK; CKBB; HEL-211; HEL-S-29;
Alternate namescreatine kinase B-type; creatine kinase-B; creatine kinase B chain; epididymis luminal protein 211; epididymis secretory protein Li 29;
Chromosome14
Map Location14q32
EC Number2.7.3.2
SummaryThe protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CKB

Proteins

creatine kinase B-type
Refseq ID:NP_001814
Protein GI:21536286
UniProt ID:P12277
mRNA ID:NM_001823
Length:381
RefSeq Status:
MPFSNSHNALKLRFPAEDEFPDLSAHNNHMAKVLTPELYAELRAKSTPSGFTLDDVIQTGVDNPGHPYIMTVGCVAGDEESYEVFKDLFDPIIEDRHGGY
KPSDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKPVSP
LLLASGMARDWPDARGIWHNDNKTFLVWVNEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKDYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP
NLGKHEKFSEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK