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MitoProteome Human Mitochondrial Protein Database
MitoProteome Database
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Related Proteins
MT000121
Gene Information
Entrez Gene ID
1173
Gene Name
adaptor-related protein complex 2, mu 1 subunit
Gene Symbol
AP2M1
Species
Homo sapiens
Gene Ontology (GO Annotations)
GO ID
Source
Type
Description
GO:0030131
IEA:InterPro
C
clathrin adaptor complex
GO:0030669
TAS:Reactome
C
clathrin-coated endocytic vesicle membrane
GO:0005905
IEA:UniProtKB-KW
C
coated pit
GO:0005829
TAS:Reactome
C
cytosol
GO:0030666
TAS:Reactome
C
endocytic vesicle membrane
GO:0070062
IDA:UniProt
C
extracellular vesicular exosome
GO:0005765
TAS:Reactome
C
lysosomal membrane
GO:0005739
IEA:Ensembl
C
mitochondrion
GO:0005886
TAS:Reactome
C
plasma membrane
GO:0008289
IEA:UniProtKB-KW
F
lipid binding
GO:0005215
TAS:ProtInc
F
transporter activity
GO:0019886
TAS:Reactome
P
antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0007411
TAS:Reactome
P
axon guidance
GO:0006897
IEA:UniProtKB-KW
P
endocytosis
GO:0007173
TAS:Reactome
P
epidermal growth factor receptor signaling pathway
GO:0006886
IEA:InterPro
P
intracellular protein transport
GO:0061024
TAS:Reactome
P
membrane organization
GO:0042059
TAS:Reactome
P
negative regulation of epidermal growth factor receptor signaling pathway
GO:1903077
IMP:UniProtKB
P
negative regulation of protein localization to plasma membrane
GO:0048011
TAS:Reactome
P
neurotrophin TRK receptor signaling pathway
GO:0050690
TAS:Reactome
P
regulation of defense response to virus by virus
GO:0007268
TAS:Reactome
P
synaptic transmission
GO:0016032
TAS:Reactome
P
viral process
KEGG Pathway Links
KEGG Pathway ID
Description
hsa04961
Endocrine and other factor-regulated calcium reabsorption
ko04961
Endocrine and other factor-regulated calcium reabsorption
hsa04144
Endocytosis
ko04144
Endocytosis
hsa05016
Huntington's disease
ko05016
Huntington's disease
hsa04721
Synaptic vesicle cycle
ko04721
Synaptic vesicle cycle
REACTOME Pathway Links
REACTOME Pathway ID
Description
REACT_75774
Adaptive Immune System
REACT_18266
Axon guidance
REACT_172694
beta-catenin independent WNT signaling
REACT_111045
Developmental Biology
REACT_116125
Disease
REACT_12484
EGFR downregulation
REACT_228189
EPH-ephrin mediated repulsion of cells
REACT_228170
EPH-Ephrin signaling
REACT_11049
Formation of annular gap junctions
REACT_11035
Gap junction degradation
REACT_9411
Gap junction trafficking
REACT_9480
Gap junction trafficking and regulation
REACT_18347
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
REACT_6185
HIV Infection
REACT_6288
Host Interactions of HIV factors
REACT_6900
Immune System
REACT_22205
L1CAM interactions
REACT_11123
Membrane Trafficking
REACT_121399
MHC class II antigen presentation
REACT_11166
Nef Mediated CD4 Down-regulation
REACT_11200
Nef Mediated CD8 Down-regulation
REACT_11139
Nef mediated downregulation of CD28 cell surface expression
REACT_11149
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
REACT_13685
Neuronal System
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_12056
NGF signalling via TRKA from the plasma membrane
REACT_172581
PCP/CE pathway
REACT_22365
Recycling pathway of L1
REACT_12435
Retrograde neurotrophin signalling
REACT_9417
Signaling by EGFR
REACT_115871
Signaling by EGFR in Cancer
REACT_11045
Signaling by Wnt
REACT_11061
Signalling by NGF
REACT_111102
Signal Transduction
REACT_6835
The role of Nef in HIV-1 replication and disease pathogenesis
REACT_18307
Trafficking of AMPA receptors
REACT_18422
Trafficking of GluR2-containing AMPA receptors
REACT_13477
Transmission across Chemical Synapses
REACT_172631
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
REACT_172599
WNT5A-dependent internalization of FZD4
MitoProteome Human Mitochondrial Protein Database
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