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MitoProteome Human Mitochondrial Protein Database
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Related Proteins
MT000126
Gene Information
Entrez Gene ID
1213
Gene Name
clathrin, heavy chain (Hc)
Gene Symbol
CLTC
Species
Homo sapiens
Gene Ontology (GO Annotations)
GO ID
Source
Type
Description
GO:0030118
NAS:UniProtKB
C
clathrin coat
GO:0030669
TAS:Reactome
C
clathrin-coated endocytic vesicle membrane
GO:0030136
IDA:UniProtKB
C
clathrin-coated vesicle
GO:0030132
IEA:InterPro
C
clathrin coat of coated pit
GO:0030130
IEA:InterPro
C
clathrin coat of trans-Golgi network vesicle
GO:0071439
IDA:FlyBase
C
clathrin complex
GO:0005829
TAS:Reactome
C
cytosol
GO:0070062
IDA:UniProtKB
C
extracellular vesicular exosome
GO:0005925
IDA:UniProtKB
C
focal adhesion
GO:0016020
IDA:UniProtKB
C
membrane
GO:0005739
IEA:Ensembl
C
mitochondrion
GO:0005886
TAS:Reactome
C
plasma membrane
GO:0043234
IDA:MGI
C
protein complex
GO:0005819
IDA:UniProtKB
C
spindle
GO:0032588
TAS:Reactome
C
trans-Golgi network membrane
GO:0031982
IDA:UniProtKB
C
vesicle
GO:0032051
IPI:FlyBase
F
clathrin light chain binding
GO:0003725
IDA:MGI
F
double-stranded RNA binding
GO:0044822
IDA:UniProtKB
F
poly(A) RNA binding
GO:0019901
ISS:ParkinsonsUK-UCL
F
protein kinase binding
GO:0005198
NAS:UniProtKB
F
structural molecule activity
GO:0019886
TAS:Reactome
P
antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0006886
NAS:UniProtKB
P
intracellular protein transport
GO:0061024
TAS:Reactome
P
membrane organization
GO:0007067
IMP:UniProtKB
P
mitotic nuclear division
GO:1900126
IDA:UniProtKB
P
negative regulation of hyaluronan biosynthetic process
GO:1903077
IMP:UniProtKB
P
negative regulation of protein localization to plasma membrane
GO:0001649
IDA:UniProt
P
osteoblast differentiation
GO:0006892
TAS:Reactome
P
post-Golgi vesicle-mediated transport
GO:0031623
IMP:BHF-UCL
P
receptor internalization
GO:0006898
IMP:UniProtKB
P
receptor-mediated endocytosis
GO:0033572
IMP:BHF-UCL
P
transferrin transport
KEGG Pathway Links
KEGG Pathway ID
Description
hsa05100
Bacterial invasion of epithelial cells
ko05100
Bacterial invasion of epithelial cells
hsa04961
Endocrine and other factor-regulated calcium reabsorption
ko04961
Endocrine and other factor-regulated calcium reabsorption
hsa04144
Endocytosis
ko04144
Endocytosis
hsa05016
Huntington's disease
ko05016
Huntington's disease
hsa04142
Lysosome
ko04142
Lysosome
hsa04721
Synaptic vesicle cycle
ko04721
Synaptic vesicle cycle
REACTOME Pathway Links
REACTOME Pathway ID
Description
REACT_75774
Adaptive Immune System
REACT_18266
Axon guidance
REACT_172694
beta-catenin independent WNT signaling
REACT_19187
Clathrin derived vesicle budding
REACT_111045
Developmental Biology
REACT_228189
EPH-ephrin mediated repulsion of cells
REACT_228170
EPH-Ephrin signaling
REACT_11049
Formation of annular gap junctions
REACT_11035
Gap junction degradation
REACT_9411
Gap junction trafficking
REACT_9480
Gap junction trafficking and regulation
REACT_19400
Golgi Associated Vesicle Biogenesis
REACT_6900
Immune System
REACT_19287
Lysosome Vesicle Biogenesis
REACT_11123
Membrane Trafficking
REACT_121399
MHC class II antigen presentation
REACT_172581
PCP/CE pathway
REACT_11045
Signaling by Wnt
REACT_111102
Signal Transduction
REACT_11235
trans-Golgi Network Vesicle Budding
REACT_172631
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
REACT_172599
WNT5A-dependent internalization of FZD4
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