MitoProteome Database

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MT000129

Gene Information

Entrez Gene ID1327
Gene Namecytochrome c oxidase subunit IV isoform 1
Gene SymbolCOX4I1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtCextracellular vesicular exosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005743 TAS:ReactomeCmitochondrial inner membrane
GO:0005739 IDA:UniProtCmitochondrion
GO:0005634 IDA:HPACnucleus
GO:0004129 TAS:ProtIncFcytochrome-c oxidase activity
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0006091 TAS:ProtIncPgeneration of precursor metabolites and energy
GO:1902600 TAS:GOCPhydrogen ion transmembrane transport
GO:0022904 TAS:ReactomePrespiratory electron transport chain
GO:0007584 IEA:EnsemblPresponse to nutrient
GO:0044281 TAS:ReactomePsmall molecule metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa05010Alzheimer's disease
ko05010Alzheimer's disease
hsa04260Cardiac muscle contraction
ko04260Cardiac muscle contraction
hsa_M00154Cytochrome c oxidase
M00154Cytochrome c oxidase
hsa05016Huntington's disease
ko05016Huntington's disease
hsa01100Metabolic pathways
hsa04932Non-alcoholic fatty liver disease (NAFLD)
ko04932Non-alcoholic fatty liver disease (NAFLD)
hsa00190Oxidative phosphorylation
ko00190Oxidative phosphorylation
hsa05012Parkinson's disease
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_22393Respiratory electron transport
REACT_6305Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
REACT_111083The citric acid (TCA) cycle and respiratory electron transport