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MitoProteome Human Mitochondrial Protein Database
MitoProteome Database
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Domain Information
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UniProt Annotations
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Related Proteins
MT000157
Gene Information
Entrez Gene ID
1508
Gene Name
cathepsin B
Gene Symbol
CTSB
Species
Homo sapiens
Gene Ontology (GO Annotations)
GO ID
Source
Type
Description
GO:0036021
TAS:Reactome
C
endolysosome lumen
GO:0005576
TAS:Reactome
C
extracellular region
GO:0005615
IDA:BHF-UCL
C
extracellular space
GO:0070062
IDA:UniProtKB
C
extracellular vesicular exosome
GO:0005622
TAS:ProtInc
C
intracellular
GO:0043231
IDA:HPA
C
intracellular membrane-bounded organelle
GO:0005764
IDA:UniProtKB
C
lysosome
GO:0005739
IEA:Ensembl
C
mitochondrion
GO:0005730
IDA:HPA
C
nucleolus
GO:0048471
IDA:UniProtKB
C
perinuclear region of cytoplasm
GO:0005518
IDA:BHF-UCL
F
collagen binding
GO:0004197
IDA:BHF-UCL
F
cysteine-type endopeptidase activity
GO:0008234
IDA:UniProtKB
F
cysteine-type peptidase activity
GO:0008233
IDA:BHF-UCL
F
peptidase activity
GO:0043394
IPI:BHF-UCL
F
proteoglycan binding
GO:0097067
IEP:UniProtKB
P
cellular response to thyroid hormone stimulus
GO:0030574
IDA:BHF-UCL
P
collagen catabolic process
GO:0046697
IEA:Ensembl
P
decidualization
GO:0030855
IEP:UniProt
P
epithelial cell differentiation
GO:0022617
TAS:Reactome
P
extracellular matrix disassembly
GO:0030198
TAS:Reactome
P
extracellular matrix organization
GO:0045087
TAS:Reactome
P
innate immune response
GO:0006508
IDA:UniProtKB
P
proteolysis
GO:0051603
IDA:BHF-UCL
P
proteolysis involved in cellular protein catabolic process
GO:0042981
TAS:UniProtKB
P
regulation of apoptotic process
GO:0050790
IEA:InterPro
P
regulation of catalytic activity
GO:0002224
TAS:Reactome
P
toll-like receptor signaling pathway
KEGG Pathway Links
KEGG Pathway ID
Description
hsa04612
Antigen processing and presentation
ko04612
Antigen processing and presentation
hsa04142
Lysosome
ko04142
Lysosome
REACTOME Pathway Links
REACTOME Pathway ID
Description
REACT_75774
Adaptive Immune System
REACT_150180
Assembly of collagen fibrils and other multimeric structures
REACT_150401
Collagen degradation
REACT_120729
Collagen formation
REACT_118572
Degradation of the extracellular matrix
REACT_118779
Extracellular matrix organization
REACT_6900
Immune System
REACT_6802
Innate Immune System
REACT_121399
MHC class II antigen presentation
REACT_6966
Toll-Like Receptors Cascades
REACT_118632
Trafficking and processing of endosomal TLR
MitoProteome Human Mitochondrial Protein Database
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