MitoProteome Database

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MT000160

Gene Information

Entrez Gene ID1535
Gene Namecytochrome b-245, alpha polypeptide
Gene SymbolCYBA
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016324 IEA:EnsemblCapical plasma membrane
GO:0030425 IEA:EnsemblCdendrite
GO:0005794 IEA:EnsemblCGolgi apparatus
GO:0016020 IDA:UniProtKBCmembrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0043020 IDA:BHF-UCLCNADPH oxidase complex
GO:0043025 IEA:EnsemblCneuronal cell body
GO:0030670 TAS:ReactomeCphagocytic vesicle membrane
GO:0030141 TAS:BHF-UCLCsecretory granule
GO:0009055 TAS:UniProtKBFelectron carrier activity
GO:0020037 IEA:InterProFheme binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0046982 IPI:BHF-UCLFprotein heterodimerization activity
GO:0017124 IPI:BHF-UCLFSH3 domain binding
GO:0016175 IEA:EnsemblFsuperoxide-generating NADPH oxidase activity
GO:0042590 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0071230 IEA:EnsemblPcellular response to amino acid stimulus
GO:0071480 IEA:EnsemblPcellular response to gamma radiation
GO:0071333 IEA:EnsemblPcellular response to glucose stimulus
GO:0071260 IEA:EnsemblPcellular response to mechanical stimulus
GO:0071407 IEA:EnsemblPcellular response to organic cyclic compound
GO:0071356 IEA:EnsemblPcellular response to tumor necrosis factor
GO:0017004 IDA:BHF-UCLPcytochrome complex assembly
GO:0050665 ISS:BHF-UCLPhydrogen peroxide biosynthetic process
GO:0006954 IMP:BHF-UCLPinflammatory response
GO:0045087 IMP:BHF-UCLPinnate immune response
GO:0051701 TAS:ReactomePinteraction with host
GO:0003106 IEA:EnsemblPnegative regulation of glomerular filtration by angiotensin
GO:0055114 IMP:BHF-UCLPoxidation-reduction process
GO:0090382 TAS:ReactomePphagosome maturation
GO:0030307 IEA:EnsemblPpositive regulation of cell growth
GO:0001938 IEA:EnsemblPpositive regulation of endothelial cell proliferation
GO:0045730 IMP:BHF-UCLPrespiratory burst
GO:0042493 IEA:EnsemblPresponse to drug
GO:0070555 IEA:EnsemblPresponse to interleukin-1
GO:0031667 IEA:EnsemblPresponse to nutrient levels
GO:0014895 ISS:BHF-UCLPsmooth muscle hypertrophy
GO:0042554 IMP:BHF-UCLPsuperoxide anion generation
GO:0006801 IMP:BHF-UCLPsuperoxide metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa05140Leishmaniasis
ko05140Leishmaniasis
hsa04670Leukocyte transendothelial migration
ko04670Leukocyte transendothelial migration
hsa04380Osteoclast differentiation
ko04380Osteoclast differentiation
hsa04145Phagosome
ko04145Phagosome
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_111119Antigen processing-Cross presentation
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_111174Cross-presentation of particulate exogenous antigens (phagosomes)
REACT_116125Disease
REACT_6900Immune System
REACT_121237Latent infection of Homo sapiens with Mycobacterium tuberculosis
REACT_121256Phagosomal maturation (early endosomal stage)
REACT_12529Signaling by VEGF
REACT_111102Signal Transduction
REACT_228166VEGFA-VEGFR2 Pathway