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MT000162

Record overview

MITO IDMT000162
Gene ID1537
SpeciesHomo sapiens (Human)
Gene Namecytochrome c-1
Gene SymbolCYC1
SynonymsUQCR4; MC3DN6;
Alternate namescytochrome c1, heme protein, mitochondrial; complex III subunit 4; complex III subunit IV; cytochrome b-c1 complex subunit 4; ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit;
Chromosome8
Map Location8q24.3
SummaryThis gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6. [provided by RefSeq, Dec 2013]
OrthologsView orthologs and multiple alignments for CYC1

Proteins

cytochrome c1, heme protein, mitochondrial precursor
Refseq ID:NP_001907
Protein GI:21359867
UniProt ID:P08574
mRNA ID:NM_001916
Length:325
RefSeq Status:
MAAAAASLRGVVLGPRGAGLPGARARGLLCSARPGQLPLRTPQAVALSSKSGLSRGRKVMLSALGMLAAGGAGLAVALHSAVSASDLELHPPSYPWSHRG
LLSSLDHTSIRRGFQVYKQVCASCHSMDFVAYRHLVGVCYTEDEAKELAAEVEVQDGPNEDGEMFMRPGKLFDYFPKPYPNSEAARAANNGALPPDLSYI
VRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIAMAPPIYTDVLEFDDGTPATMSQIAKDVCTFLRWASEPEHDHRKRMGLKMLMMMALLV
PLVYTIKRHKWSVLKSRKLAYRPPK
 
N
transit_peptide: 1..84
experiment: experimental evidence, no additional details recorded
note: Mitochondrion; propagated from UniProtKB/Swiss-Prot (P08574.3)
calculated_mol_wt: 8056
peptide sequence: 
MAAAAASLRGVVLGPRGAGLPGARARGLLCSARPGQLPLRTPQAVALSSKSGLSRGRKVMLSALGMLAAGGAGLAVALHSAVSA

mat_peptide: 85..325
product: Cytochrome c1, heme protein, mitochondrial
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P08574.3)
calculated_mol_wt: 27353
peptide sequence: 
SDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCASCHSMDFVAYRHLVGVCYTEDEAKELAAEVEVQDGPNEDGEMFMRPGKLFDYFPKPYPNSEA
ARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIAMAPPIYTDVLEFDDGTPATMSQIAKDVCTFLRWASEPEHDH
RKRMGLKMLMMMALLVPLVYTIKRHKWSVLKSRKLAYRPPK