MitoProteome Database

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MT000165

Gene Information

Entrez Gene ID1565
Gene Namecytochrome P450, family 2, subfamily D, polypeptide 6
Gene SymbolCYP2D6
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 TAS:BHF-UCLCendoplasmic reticulum
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0005739 IDA:BHF-UCLCmitochondrion
GO:0070330 IEA:UniProtKB-ECFaromatase activity
GO:0008144 IDA:BHF-UCLFdrug binding
GO:0020037 IDA:UniProtKBFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0004497 IDA:BHF-UCLFmonooxygenase activity
GO:0016491 IDA:BHF-UCLFoxidoreductase activity
GO:0009822 IDA:BHF-UCLPalkaloid catabolic process
GO:0009820 IDA:BHF-UCLPalkaloid metabolic process
GO:0009804 IDA:BHF-UCLPcoumarin metabolic process
GO:0042737 IDA:BHF-UCLPdrug catabolic process
GO:0017144 IDA:BHF-UCLPdrug metabolic process
GO:0046483 IDA:BHF-UCLPheterocycle metabolic process
GO:0033076 IDA:BHF-UCLPisoquinoline alkaloid metabolic process
GO:0016098 IDA:BHF-UCLPmonoterpenoid metabolic process
GO:0051100 IDA:BHF-UCLPnegative regulation of binding
GO:0090350 IDA:BHF-UCLPnegative regulation of cellular organofluorine metabolic process
GO:0055114 IDA:BHF-UCLPoxidation-reduction process
GO:0070989 IDA:BHF-UCLPoxidative demethylation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0008202 IMP:BHF-UCLPsteroid metabolic process
GO:0006805 TAS:BHF-UCLPxenobiotic metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00982Drug metabolism - cytochrome P450
ko00982Drug metabolism - cytochrome P450
hsa00980Metabolism of xenobiotics by cytochrome P450
ko00980Metabolism of xenobiotics by cytochrome P450
hsa04726Serotonergic synapse
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_13797CYP2E1 reactions
REACT_13567Cytochrome P450 - arranged by substrate type
REACT_13814Fatty acids
REACT_111217Metabolism
REACT_13425Miscellaneous substrates
REACT_13705Phase 1 - Functionalization of compounds
REACT_13543Xenobiotics