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MitoProteome Human Mitochondrial Protein Database
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Related Proteins
MT000166
Gene Information
Entrez Gene ID
1571
Gene Name
cytochrome P450, family 2, subfamily E, polypeptide 1
Gene Symbol
CYP2E1
Species
Homo sapiens
Gene Ontology (GO Annotations)
GO ID
Source
Type
Description
GO:0005789
TAS:Reactome
C
endoplasmic reticulum membrane
GO:0000139
IEA:Ensembl
C
Golgi membrane
GO:0031227
IEA:Ensembl
C
intrinsic component of endoplasmic reticulum membrane
GO:0005739
IEA:Ensembl
C
mitochondrion
GO:0019899
IPI:BHF-UCL
F
enzyme binding
GO:0020037
IDA:UniProtKB
F
heme binding
GO:0005506
IEA:InterPro
F
iron ion binding
GO:0004497
IDA:BHF-UCL
F
monooxygenase activity
GO:0016491
IDA:BHF-UCL
F
oxidoreductase activity
GO:0016709
TAS:UniProtKB
F
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0016712
IEA:Ensembl
F
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019825
TAS:ProtInc
F
oxygen binding
GO:0017144
IDA:BHF-UCL
P
drug metabolic process
GO:0046483
IDA:BHF-UCL
P
heterocycle metabolic process
GO:0016098
IDA:BHF-UCL
P
monoterpenoid metabolic process
GO:0055114
IDA:BHF-UCL
P
oxidation-reduction process
GO:0042493
IEA:Ensembl
P
response to drug
GO:0045471
IEA:Ensembl
P
response to ethanol
GO:0010243
IEA:Ensembl
P
response to organonitrogen compound
GO:0010193
IEA:Ensembl
P
response to ozone
GO:0044281
TAS:Reactome
P
small molecule metabolic process
GO:0008202
IMP:BHF-UCL
P
steroid metabolic process
GO:0006641
IEA:Ensembl
P
triglyceride metabolic process
GO:0006805
TAS:Reactome
P
xenobiotic metabolic process
KEGG Pathway Links
KEGG Pathway ID
Description
hsa00590
Arachidonic acid metabolism
ko00590
Arachidonic acid metabolism
hsa05204
Chemical carcinogenesis
ko05204
Chemical carcinogenesis
hsa00982
Drug metabolism - cytochrome P450
ko00982
Drug metabolism - cytochrome P450
hsa00591
Linoleic acid metabolism
ko00591
Linoleic acid metabolism
hsa01100
Metabolic pathways
hsa00980
Metabolism of xenobiotics by cytochrome P450
ko00980
Metabolism of xenobiotics by cytochrome P450
hsa04932
Non-alcoholic fatty liver disease (NAFLD)
ko04932
Non-alcoholic fatty liver disease (NAFLD)
hsa00140
Steroid hormone biosynthesis
ko00140
Steroid hormone biosynthesis
BIOCYC Pathway Links
BIOCYC Pathway ID
Description
PWY-5451
acetone degradation I (to methylglyoxal)
PWY-5451
acetone degradation I (to methylglyoxal)
PWY66-161
ethanol degradation III (oxidative)
PWY-5453
methylglyoxal degradation III
PWY-5453
methylglyoxal degradation III
PWY66-161
oxidative ethanol degradation III
REACTOME Pathway Links
REACTOME Pathway ID
Description
REACT_13433
Biological oxidations
REACT_13797
CYP2E1 reactions
REACT_13567
Cytochrome P450 - arranged by substrate type
REACT_111217
Metabolism
REACT_13705
Phase 1 - Functionalization of compounds
REACT_13543
Xenobiotics
MitoProteome Human Mitochondrial Protein Database
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