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MT000697

Record overview

MITO IDMT000697
Gene ID9140
SpeciesHomo sapiens (Human)
Gene Nameautophagy related 12
Gene SymbolATG12
SynonymsAPG12; FBR93; APG12L; HAPG12;
Alternate namesubiquitin-like protein ATG12; Apg12 (autophagy, yeast) homolog; ATG12 autophagy related 12 homolog;
Chromosome5
Map Location5q21-q22
SummaryAutophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for ATG12

Proteins

ubiquitin-like protein ATG12 isoform 1
Refseq ID:NP_004698
Protein GI:290560746
UniProt ID:O94817
mRNA ID:NM_004707
Length:140
RefSeq Status:
MAEEPQSVLQLPTSIAAGGEGLTDVSPETTTPEPPSSAAVSPGTEEPAGDTKKKIDILLKAVGDTPIMKTKKWAVERTRTIQGLIDFIKKFLKLVASEQL
FIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG
 
ubiquitin-like protein ATG12 isoform 2
Refseq ID:NP_001264712
Protein GI:480540330
UniProt ID:O94817
mRNA ID:NM_001277783
Length:74
RefSeq Status:
MAEEPQSVLQLPTSIAAGGEGLTDVSPETTTPEPPSSAAVSPGTEEPAGDTKKKIYLCESVLCSFPRPRSWNSL