MitoProteome Database

MT000718

Record overview

MITO ID	MT000718
Gene ID	9529
Species	Homo sapiens (Human)
Gene Name	BCL2-associated athanogene 5
Gene Symbol	BAG5
Synonyms	BAG-5;
Alternate names	BAG family molecular chaperone regulator 5; bcl-2-associated athanogene 5; BAG-family molecular chaperone regulator-5;
Chromosome	14
Map Location	14q32.33
Summary	The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Orthologs	View orthologs and multiple alignments for BAG5

Proteins

BAG family molecular chaperone regulator 5 isoform a

Refseq ID:	NP_001015049
Protein GI:	62548856
UniProt ID:	Q9UL15
mRNA ID:	NM_001015049
Length:	488
RefSeq Status:

MRFHWLPTLSEPFDRNQELETCIRPLWTPSGSACETEHNKSMDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTE
GKGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNIFEEAQSLVREKIVPFYNGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAV
QEIIEDCMKKQPSLPLSEDAHPSVAKINFVMCEVNKARGVLIALLMGVNNNETCRHLSCVLSGLIADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLE
EEADTTKAFDLRQNHSILKIEKVLKRMREIKNELLQAQNPSELYLSSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYIDLKEALEKRKLFA
CEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDKNYIRLEELLTKQLLALDAVDPQGEEKCKAARKQAVRLAQNILSYLDLKSDEWEY

BAG family molecular chaperone regulator 5 isoform b

Refseq ID:	NP_001015048
Protein GI:	62548854
UniProt ID:	Q9UL15
mRNA ID:	NM_001015048
Length:	447
RefSeq Status:

MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNIFEE
AQSLVREKIVPFYNGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCMKKQPSLPLSEDAHPSVAKINFVMCEVNKARGVL
IALLMGVNNNETCRHLSCVLSGLIADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADTTKAFDLRQNHSILKIEKVLKRMREIKNELLQAQNPS
ELYLSSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDKNYIRLEE
LLTKQLLALDAVDPQGEEKCKAARKQAVRLAQNILSYLDLKSDEWEY

BAG family molecular chaperone regulator 5 isoform b

Refseq ID:	NP_004864
Protein GI:	6631077
UniProt ID:	Q9UL15
mRNA ID:	NM_004873
Length:	447
RefSeq Status:

Protein sequence is identical to GI:62548854 (mRNA isoform)