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MT000778

Record overview

MITO IDMT000778
Gene ID10449
SpeciesHomo sapiens (Human)
Gene Nameacetyl-CoA acyltransferase 2
Gene SymbolACAA2
SynonymsDSAEC;
Alternate names3-ketoacyl-CoA thiolase, mitochondrial; T1; beta ketothiolase; beta-ketothiolase; acetyl-Coenzyme A acyltransferase 2; mitochondrial 3-oxoacyl-CoA thiolase; mitochondrial 3-oxoacyl-Coenzyme A thiolase;
Chromosome18
Map Location18q21.1
EC Number2.3.1.16
SummaryThe encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ACAA2

Proteins

3-ketoacyl-CoA thiolase, mitochondrial
Refseq ID:NP_006102
Protein GI:167614485
UniProt ID:P42765
mRNA ID:NM_006111
Length:397
RefSeq Status:
MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIV
NGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFN
DEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI
SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA