MitoProteome Database

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MT000778

UniProt Annotations

Entry Information
Gene Nameacetyl-CoA acyltransferase 2
Protein EntryTHIM_HUMAN
UniProt IDP42765
SpeciesHuman
Comments
Comment typeDescription
Catalytic Activity Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
Function Abolishes BNIP3-mediated apoptosis and mitochondrial damage. {ECO:0000269|PubMed:18371312}.
Pathway Lipid metabolism; fatty acid metabolism.
Similarity Belongs to the thiolase family. {ECO:0000305}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:18371312}. Note=Colocalizes with BNIP3 in the mitochondria.
Subunit Homotetramer. Interacts with BNIP3. {ECO:0000269|PubMed:18371312}.