MitoProteome Database

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MT000836

UniProt Annotations

Entry Information

Gene Name	chromosome 10 open reading frame 10
Protein Entry	DEPP_HUMAN
UniProt ID	Q9NTK1
Species	Human

Comments

Comment type	Description
Developmental Stage	High levels in first trimester deciduas. Higher levels in the endometria during secretory phase than the proliferative phase, especially after the mid-secretory phase. {ECO:0000269\|PubMed:16123073}.
Function	May play a role in autophagy. {ECO:0000269\|PubMed:24530860}.
Induction	By progesterone, testosterone and, to a much lower extent, estrogen. Up-regulated by hypoxia (at protein level). {ECO:0000269\|PubMed:16123073, ECO:0000269\|PubMed:21510935}.
Sequence Caution	Sequence=CAI13066.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Subcellular Location	Cytoplasm {ECO:0000269\|PubMed:24530860}. Note=May localize to aggresomes.
Tissue Specificity	Expressed in various tissues, including pancreas, placenta, ovary, testis and kidney. {ECO:0000269\|PubMed:16123073}.