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MT000895

Record overview

MITO IDMT000895
Gene ID23564
SpeciesHomo sapiens (Human)
Gene Namedimethylarginine dimethylaminohydrolase 2
Gene SymbolDDAH2
SynonymsG6a; DDAH; NG30; DDAHII; HEL-S-277;
Alternate namesN(G),N(G)-dimethylarginine dimethylaminohydrolase 2; S-phase protein; dimethylargininase-2; epididymis secretory protein Li 277; dimethylarginine dimethylaminohydrolase II;
Chromosome6
Map Location6p21.3
EC Number3.5.3.18
SummaryThis gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants. [provided by RefSeq, Dec 2014]
OrthologsView orthologs and multiple alignments for DDAH2

Proteins

N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
Refseq ID:NP_001289936
Protein GI:731441424
UniProt ID:
mRNA ID:NM_001303007
Length:285
RefSeq Status:
MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEV
DGVRKALQDLGLRIVEIGDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVAGSSDAAQKAVRAMA
VLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGGDLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
 
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
Refseq ID:NP_001289937
Protein GI:731441427
UniProt ID:
mRNA ID:NM_001303008
Length:285
RefSeq Status:
Protein sequence is identical to GI:731441424 (mRNA isoform)
 
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
Refseq ID:NP_039268
Protein GI:7524354
UniProt ID:O95865
mRNA ID:NM_013974
Length:285
RefSeq Status:
Protein sequence is identical to GI:731441424 (mRNA isoform)