MitoProteome Database

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MT001178

UniProt Annotations

Entry Information

Gene Name	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
Protein Entry	DDX28_HUMAN
UniProt ID	Q9NUL7
Species	Human

Comments

Comment type	Description
Catalytic Activity	ATP + H(2)O = ADP + phosphate.
Function	May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity. {ECO:0000269\|PubMed:11350955}.
Similarity	Belongs to the DEAD box helicase family. {ECO:0000305}.
Similarity	Contains 1 helicase ATP-binding domain. {ECO:0000255\|PROSITE-ProRule:PRU00541}.
Similarity	Contains 1 helicase C-terminal domain. {ECO:0000255\|PROSITE-ProRule:PRU00542}.
Subcellular Location	Nucleus {ECO:0000269\|PubMed:11350955}. Mitochondrion {ECO:0000269\|PubMed:11350955}. Note=Transported between these two compartments. Nuclear localization depends on active RNA polymerase II transcription.
Tissue Specificity	Expressed in all tissues tested, including brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, leukocytes, colon, small intestine, ovary and prostate. {ECO:0000269\|PubMed:11350955}.