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MT001220

Record overview

MITO IDMT001220
Gene ID57412
SpeciesHomo sapiens (Human)
Gene Namearsenite methyltransferase
Gene SymbolAS3MT
SynonymsCYT19;
Alternate namesarsenite methyltransferase; methyltransferase cyt19; methylarsonite methyltransferase; arsenic (+3 oxidation state) methyltransferase; S-adenosylmethionine:arsenic (III) methyltransferase; S-adenosyl-L-methionine:arsenic(III) methyltransferase;
Chromosome10
Map Location10q24.32
EC Number2.1.1.137
SummaryAS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for AS3MT

Proteins

arsenite methyltransferase
Refseq ID:NP_065733
Protein GI:109389364
UniProt ID:Q9HBK9
mRNA ID:NM_020682
Length:375
RefSeq Status:
MAALRDAEIQKDVQTYYGQVLKRSADLQTNGCVTTARPVPKHIREALQNVHEEVALRYYGCGLVIPEHLENCWILDLGSGSGRDCYVLSQLVGEKGHVTG
IDMTKGQVEVAEKYLDYHMEKYGFQASNVTFIHGYIEKLGEAGIKNESHDIVVSNCVINLVPDKQQVLQEAYRVLKHGGELYFSDVYTSLELPEEIRTHK
VLWGECLGGALYWKELAVLAQKIGFCPPRLVTANLITIQNKELERVIGDCRFVSATFRLFKHSKTGPTKRCQVIYNGGITGHEKELMFDANFTFKEGEIV
EVDEETAAILKNSRFAQDFLIRPIGEKLPTSGGCSALELKDIITDPFKLAEESDSMKSRCVPDAAGGCCGTKKSC