MitoProteome Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins

MT001382

Record overview

MITO ID	MT001382
Gene ID	83787
Species	Homo sapiens (Human)
Gene Name	armadillo repeat containing 10
Gene Symbol	ARMC10
Synonyms	SVH; PNAS112; PNAS-112; PSEC0198;
Alternate names	armadillo repeat-containing protein 10; splicing variant involved in hepatocarcinogenesis protein; specific splicing variant involved in hepatocarcinogenesis;
Chromosome	7
Map Location	7q22.1
Summary	This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]
Orthologs	View orthologs and multiple alignments for ARMC10

Proteins

armadillo repeat-containing protein 10 isoform a

Refseq ID:	NP_114111
Protein GI:	31377663
UniProt ID:	Q8N2F6
mRNA ID:	NM_031905
Length:	343
RefSeq Status:

armadillo repeat-containing protein 10 isoform b
`MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSSKSAGALEEGTSEGQLCGRSARPQTGGTWESQWSKTSQPEDLTDGSYDDVLNAEQLQK LLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGL TLLTNMTVTNDHQHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEGHLAVQ PTFTEGSLFFLLHGEECAQKIRALVDHHDAEVKEKVVTIIPKI`

Refseq ID:	NP_001154481
Protein GI:	238776793
UniProt ID:	Q8N2F6
mRNA ID:	NM_001161009
Length:	308
RefSeq Status:

armadillo repeat-containing protein 10 isoform c
`MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSSKSAEDLTDGSYDDVLNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIR ELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDHQHMLHSYITDLFQVLLTGNGNTK VQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVDHHDAEVKEK VVTIIPKI`

Refseq ID:	NP_001154482
Protein GI:	238776795
UniProt ID:	Q8N2F6
mRNA ID:	NM_001161010
Length:	284
RefSeq Status:

armadillo repeat-containing protein 10 isoform d
`MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSSKSAGALEEGTSEGQLCGRSARPQTGGTWESQWSKTSQPEDLTDGSYDDVLNAEQLQK LLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKVQVLKLLLNLSENPAMTEGLLRAQ VDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVDHHDAEVKEKVVTIIPKI`

Refseq ID:	NP_001154484
Protein GI:	238776799
UniProt ID:	Q8N2F6
mRNA ID:	NM_001161012
Length:	249
RefSeq Status:

armadillo repeat-containing protein 10 isoform e
`MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSSKSAEDLTDGSYDDVLNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIR ELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIE GHLAVQPTFTEGSLFFLLHGEECAQKIRALVDHHDAEVKEKVVTIIPKI`

Refseq ID:	NP_001154483
Protein GI:	238776797
UniProt ID:	Q8N2F6
mRNA ID:	NM_001161011
Length:	284
RefSeq Status:

armadillo repeat-containing protein 10 isoform f
`MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSSKSAEDLTDGSYDDVLNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIR ELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDHQHMLHSYITDLFQVLLTGNGNTK VDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVDHHDAEVKEKVVTIIPKI`

Refseq ID:	NP_001154485
Protein GI:	238776801
UniProt ID:	Q8N2F6
mRNA ID:	NM_001161013
Length:	225
RefSeq Status:

`MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSSKSAEDLTDGSYDDVLNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIR ELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLLHGEECA QKIRALVDHHDAEVKEKVVTIIPKI`