MitoProteome Database

MT001408

Record overview

MITO ID	MT001408
Gene ID	84334
Species	Homo sapiens (Human)
Gene Name	apoptogenic 1, mitochondrial
Gene Symbol	APOPT1
Synonyms	APOP; APOP1; C14orf153;
Alternate names	apoptogenic protein 1, mitochondrial; UPF0671 protein C14orf153;
Chromosome	14
Map Location	14q32.33
Summary	This gene encodes a protein that localizes to the mitochondria, where it stimulates the release of cytochrome c, thereby promoting programmed cell death. Mutations in this gene have been found in individuals with mitochondrial complex IV deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Orthologs	View orthologs and multiple alignments for APOPT1

Proteins

apoptogenic protein 1, mitochondrial isoform 1

Refseq ID:	NP_115750
Protein GI:	190341102
UniProt ID:	Q96IL0
mRNA ID:	NM_032374
Length:	206
RefSeq Status:

`MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQLAPERGAERRDTAPSGVSRFCPPRKSCHDWIGPPDKYSNLRPVHFYIPENESPLEQKLRKLR QETQEWNQQFWANQNLTFSKEKEEFIHSRLKTKGLGLRTESGQKATLNAEEMADFYKEFLSKNFQKHMYYNRDWYKRNFAITFFMGKVALERIWNKLKQK QKKRSN`

N
transit_peptide: 1..39
experiment: experimental evidence, no additional details recorded
note: Mitochondrion. {ECO:0000255}; propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 4092
peptide sequence: 
MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQL

mat_peptide: 40..206
product: Apoptogenic protein 1, mitochondrial
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 20079
peptide sequence: 
APERGAERRDTAPSGVSRFCPPRKSCHDWIGPPDKYSNLRPVHFYIPENESPLEQKLRKLRQETQEWNQQFWANQNLTFSKEKEEFIHSRLKTKGLGLRT
ESGQKATLNAEEMADFYKEFLSKNFQKHMYYNRDWYKRNFAITFFMGKVALERIWNKLKQKQKKRSN

apoptogenic protein 1, mitochondrial isoform 2

Refseq ID:	NP_001289581
Protein GI:	703491579
UniProt ID:
mRNA ID:	NM_001302652
Length:	196
RefSeq Status:

`MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQLAPERGAERRDTAPSGVSRFCPPRKSCHDWIGPPDKYSNLRPVHFYIPENESPLEQKLRKLR QETQEWNQQFWANQNLTFSKEKEEFIHSRLKTKGLGLRTESGQKATLNAEEMADFYKEFLSKNFQKHMYYNRLVQAQFCHHLLHGKSGPGKDLEQA`

N
transit_peptide: 1..39
experiment: experimental evidence, no additional details recorded
note: Mitochondrion. {ECO:0000255}; propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 4092
peptide sequence: 
MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQL

mat_peptide: 40..206
product: Apoptogenic protein 1, mitochondrial
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 20079
peptide sequence: 
APERGAERRDTAPSGVSRFCPPRKSCHDWIGPPDKYSNLRPVHFYIPENESPLEQKLRKLRQETQEWNQQFWANQNLTFSKEKEEFIHSRLKTKGLGLRT
ESGQKATLNAEEMADFYKEFLSKNFQKHMYYNRDWYKRNFAITFFMGKVALERIWNKLKQKQKKRSN

transit_peptide: 1..39
experiment: experimental evidence, no additional details recorded
note: Mitochondrion. {ECO:0000255}; propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 4092
peptide sequence: 
MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQL

transit_peptide: 1..39
experiment: experimental evidence, no additional details recorded
note: Mitochondrion. {ECO:0000255}; propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 4092
peptide sequence: 
MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQL

transit_peptide: 1..39
experiment: experimental evidence, no additional details recorded
note: Mitochondrion. {ECO:0000255}; propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 4092
peptide sequence: 
MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQL

apoptogenic protein 1, mitochondrial isoform 3

Refseq ID:	NP_001289582
Protein GI:	703491581
UniProt ID:
mRNA ID:	NM_001302653
Length:	190
RefSeq Status:

`MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQLAPERGAERRDTAPSGVSRFCPPRKSCHDWIGPPDKYSNLRPVHFYIPENESPLEQKLRKLR QETQEWNQQFWANQNLTFSKEKEEFIHSRLKTKGLGLRTESDPTLPRVTETMERKTMDGGDSCAAAISLTQSESNIECRRNGGLLQGIFK`

N
transit_peptide: 1..39
experiment: experimental evidence, no additional details recorded
note: Mitochondrion. {ECO:0000255}; propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 4092
peptide sequence: 
MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQL

mat_peptide: 40..206
product: Apoptogenic protein 1, mitochondrial
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 20079
peptide sequence: 
APERGAERRDTAPSGVSRFCPPRKSCHDWIGPPDKYSNLRPVHFYIPENESPLEQKLRKLRQETQEWNQQFWANQNLTFSKEKEEFIHSRLKTKGLGLRT
ESGQKATLNAEEMADFYKEFLSKNFQKHMYYNRDWYKRNFAITFFMGKVALERIWNKLKQKQKKRSN

transit_peptide: 1..39
experiment: experimental evidence, no additional details recorded
note: Mitochondrion. {ECO:0000255}; propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 4092
peptide sequence: 
MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQL

apoptogenic protein 1, mitochondrial isoform 4

Refseq ID:	NP_001289583
Protein GI:	703491583
UniProt ID:
mRNA ID:	NM_001302654
Length:	146
RefSeq Status:

`MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQLAPERGAERRDTAPSGVSRFCPPRKSCHDWIGPPDKYSNLRPVHFYIPENESPLEQKLRKLR QETQEWNQQFWANQNLTFSKEKEEFIHSRLKTKGLGLRTESGGYDG`

N
transit_peptide: 1..39
experiment: experimental evidence, no additional details recorded
note: Mitochondrion. {ECO:0000255}; propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 4092
peptide sequence: 
MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQL

mat_peptide: 40..206
product: Apoptogenic protein 1, mitochondrial
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 20079
peptide sequence: 
APERGAERRDTAPSGVSRFCPPRKSCHDWIGPPDKYSNLRPVHFYIPENESPLEQKLRKLRQETQEWNQQFWANQNLTFSKEKEEFIHSRLKTKGLGLRT
ESGQKATLNAEEMADFYKEFLSKNFQKHMYYNRDWYKRNFAITFFMGKVALERIWNKLKQKQKKRSN

transit_peptide: 1..39
experiment: experimental evidence, no additional details recorded
note: Mitochondrion. {ECO:0000255}; propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 4092
peptide sequence: 
MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQL

transit_peptide: 1..39
experiment: experimental evidence, no additional details recorded
note: Mitochondrion. {ECO:0000255}; propagated from UniProtKB/Swiss-Prot (Q96IL0.3)
calculated_mol_wt: 4092
peptide sequence: 
MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQL