MitoProteome Database

MT001081

Gene Information

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	IMP:UniProtKB	C	cytosol
GO:0005743	TAS:Reactome	C	mitochondrial inner membrane
GO:0005758	TAS:UniProtKB	C	mitochondrial intermembrane space
GO:0005739	IDA:UniProt	C	mitochondrion
GO:0005634	IDA:LIFEdb	C	nucleus
GO:0000159	TAS:UniProtKB	C	protein phosphatase type 2A complex
GO:0070469	IEA:UniProtKB-KW	C	respiratory chain
GO:0045155	IDA:UniProtKB	F	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
GO:0020037	TAS:UniProtKB	F	heme binding
GO:0005506	IEA:InterPro	F	iron ion binding
GO:0008635	TAS:UniProtKB	P	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0006309	IMP:UniProtKB	P	apoptotic DNA fragmentation
GO:0006915	TAS:Reactome	P	apoptotic process
GO:0044237	TAS:Reactome	P	cellular metabolic process
GO:0045333	TAS:UniProtKB	P	cellular respiration
GO:0016311	TAS:GOC	P	dephosphorylation
GO:0097193	TAS:Reactome	P	intrinsic apoptotic signaling pathway
GO:0022904	TAS:Reactome	P	respiratory electron transport chain
GO:0044281	TAS:Reactome	P	small molecule metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
hsa05010	Alzheimer's disease
ko05010	Alzheimer's disease
hsa05014	Amyotrophic lateral sclerosis (ALS)
ko05014	Amyotrophic lateral sclerosis (ALS)
hsa04210	Apoptosis
ko04210	Apoptosis
hsa05210	Colorectal cancer
ko05210	Colorectal cancer
hsa05161	Hepatitis B
hsa05168	Herpes simplex infection
ko05168	Herpes simplex infection
hsa05016	Huntington's disease
ko05016	Huntington's disease
hsa05164	Influenza A
ko05164	Influenza A
hsa05134	Legionellosis
ko05134	Legionellosis
hsa01100	Metabolic pathways
hsa04932	Non-alcoholic fatty liver disease (NAFLD)
ko04932	Non-alcoholic fatty liver disease (NAFLD)
hsa04115	p53 signaling pathway
ko04115	p53 signaling pathway
hsa05012	Parkinson's disease
hsa05200	Pathways in cancer
hsa05222	Small cell lung cancer
ko05222	Small cell lung cancer
hsa00920	Sulfur metabolism
ko00920	Sulfur metabolism
hsa05145	Toxoplasmosis
ko05145	Toxoplasmosis
hsa05152	Tuberculosis
ko05152	Tuberculosis
hsa05416	Viral myocarditis

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_607	Activation of caspases through apoptosome-mediated cleavage
REACT_578	Apoptosis
REACT_963	Apoptotic factor-mediated response
REACT_120956	Cellular responses to stress
REACT_831	Cytochrome c-mediated apoptotic response
REACT_172715	Detoxification of Reactive Oxygen Species
REACT_89	Formation of apoptosome
REACT_964	Intrinsic Pathway for Apoptosis
REACT_111217	Metabolism
REACT_200788	Mitochondrial biogenesis
REACT_200751	Organelle biogenesis and maintenance
REACT_1322	Release of apoptotic factors from the mitochondria
REACT_22393	Respiratory electron transport
REACT_6305	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
REACT_111083	The citric acid (TCA) cycle and respiratory electron transport
REACT_200608	Transcriptional activation of mitochondrial biogenesis