MitoProteome Database

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MT001451

Gene Information

Entrez Gene ID90427
Gene NameBcl2 modifying factor
Gene SymbolBMF
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0001669 IEA:EnsemblCacrosomal vesicle
GO:0005829 TAS:ReactomeCcytosol
GO:0005741 TAS:ReactomeCmitochondrial outer membrane
GO:0016459 ISS:UniProtKBCmyosin complex
GO:0005886 TAS:ReactomeCplasma membrane
GO:0043276 IDA:MGIPanoikis
GO:0006915 TAS:ReactomePapoptotic process
GO:0097193 TAS:ReactomePintrinsic apoptotic signaling pathway
GO:2001234 IEA:EnsemblPnegative regulation of apoptotic signaling pathway
GO:2001244 TAS:ReactomePpositive regulation of intrinsic apoptotic signaling pathway
GO:0032464 ISS:BHF-UCLPpositive regulation of protein homooligomerization
GO:1900740 TAS:ReactomePpositive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:0090200 ISS:BHF-UCLPpositive regulation of release of cytochrome c from mitochondria
KEGG Pathway Links
KEGG Pathway IDDescription
hsa05206MicroRNAs in cancer
ko05206MicroRNAs in cancer
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_697Activation of BH3-only proteins
REACT_2100Activation of BMF and translocation to mitochondria
REACT_578Apoptosis
REACT_330BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
REACT_964Intrinsic Pathway for Apoptosis